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Semax — research-grade peptide, ≥98% purity
Research Use Only

Cognitive & Mood

Semax

5mg / vial

A synthetic heptapeptide analog derived from ACTH(4–10), investigated for impacts on brain blood flow, neurotrophic factors, cognitive performance, and neuroprotection. Research explores BDNF upregulation, synaptic plasticity modulation, and neuroprotective signaling in ischemia and hypoxia models.

In stock — ships same day before 1PM EST

$89.99

Size

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≥98% Purity

Third-party verified

Cold-Chain Shipping

Free on every order

COA Included

HPLC · LC-MS · NMR

Same-Day Shipping

Orders before 1PM EST

For Research Use Only. Not for human or animal consumption. Not a drug, food, or cosmetic. For in vitro laboratory research by qualified researchers only.

Areas of Investigation

Research Applications

Brain Protection

Neuroprotection

Studied for protective effects on neurons in models of stroke, traumatic brain injury, and oxidative stress.

Cognition

Cognitive Enhancement

Investigated for its effects on memory, attention, and learning through BDNF upregulation and neurotransmitter modulation.

BDNF

BDNF & Neurotrophin Research

Researched for its ability to increase brain-derived neurotrophic factor expression, supporting neuronal survival and synaptic plasticity.

Neurotransmitters

Neurotransmitter Modulation

Explored for effects on dopaminergic and serotonergic systems in preclinical models.

Technical Data

Compound Profile

Full compound characterization including molecular structure, physical properties, storage requirements, and stability data for research use.

≥98% Purity Guaranteed

HPLC · LC-MS · Third-Party Verified

Sequence

Met-Glu-His-Phe-Pro-Gly-Pro

Molecular Formula

C₃₇H₅₁N₉O₁₀S

Molecular Weight

813.93 g/mol

Appearance

White lyophilized powder

Storage (Lyophilized)

Below −20°C, desiccated, away from light and moisture

Storage (Reconstituted)

Refrigerate at 2–8°C; use within 28 days. Aliquot for extended storage below −20°C.

Shelf Life

24 months from manufacture date

Third-Party Verified

Certificate of Analysis

99.68%

PURITY

Semax · Batch A

TAP TO VIEW FULL COA

Batch Analysis Report

Lot Number

PLQ-SEMAX-2601-A

Labeled Amount

5mg

Actual Amount

5.34mg

Testing Date

01/24/2026

Tested By

Apex Analytics Lab (Third-Party)

Methods

HPLC · LC-MS · NMR · FTIR

Full COA documentation is included with every order. COAs are batch-specific and reflect the exact lot shipped. Independent third-party verification ensures unbiased purity and identity confirmation.

Protocol

Storage & Handling

Long-Term Storage

Store lyophilized peptide at −20°C. Under these conditions the product remains stable for up to 24 months from the date of manufacture.

After Reconstitution

Once reconstituted, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles as this may degrade compound integrity.

Shipping Conditions

All orders ship in insulated packaging with cooling packs to maintain the cold chain during transit. Free on every order, no minimum required.

Support

Frequently Asked Questions

Semax is a synthetic heptapeptide analog of ACTH(4-10) developed in Russia at the Institute of Molecular Genetics. Unlike ACTH, semax lacks hormonal activity and acts through CNS pathways, primarily studied for neuroprotection and cognitive effects. It reflects semax's original development context in cerebrovascular disease research.

Semax has been approved in Russia and several CIS countries for stroke and cognitive disorders treatment. It does not have FDA or EMA approval. Our research-grade semax is strictly for in vitro laboratory research. Not for human or animal consumption.

Semax acts through ACTH-related CNS pathways and is primarily studied for neuroprotection, BDNF upregulation, and cognitive enhancement. Selank is a tuftsin analog studied for immune modulation, anxiolytic, and stress adaptation effects. Together they address complementary neuroimmune pathways — which is why they are frequently co-researched.

Add bacteriostatic water slowly along the vial wall, gently swirl until dissolved. Semax dissolves readily. Use our Reconstitution Calculator for volume guidance.

Our semax is verified at ≥98% purity via third-party HPLC analysis. The current batch is confirmed at 99.68% by Apex Analytics Lab. A full COA ships with every order.

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