Cognitive & Mood
PT-141
10mg / vial
A synthetic melanocortin receptor peptide derived from alpha-MSH, studied for effects on central arousal circuits in sexual function models, cardiovascular markers, and behavioral endpoints. Functions as a melanocortin receptor agonist targeting brain regions involved in sexual response and autonomic function.
$84.99
Size
≥98% Purity
Third-party verified
Cold-Chain Shipping
Free on every order
COA Included
HPLC · LC-MS · NMR
Same-Day Shipping
Orders before 1PM EST
For Research Use Only. Not for human or animal consumption. Not a drug, food, or cosmetic. For in vitro laboratory research by qualified researchers only.
Areas of Investigation
Research Applications
Sexual Health
Sexual Function Research
FDA-approved for HSDD through MC4R/MC3R activation in the CNS, representing a unique mechanism distinct from vascular-based approaches.
Receptor Research
Melanocortin Receptor Pharmacology
Studied as a tool compound for understanding MC3R and MC4R signaling pathways in the central nervous system.
CNS Signaling
Central Nervous System Signaling
Investigated for its central mechanism of action in modulating desire and arousal through hypothalamic melanocortin circuits.
Technical Data
Compound Profile
Full compound characterization including molecular structure, physical properties, storage requirements, and stability data for research use.
≥98% Purity Guaranteed
HPLC · LC-MS · Third-Party Verified
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Molecular Formula
C₅₀H₆₈N₁₄O₁₀
Molecular Weight
1,025.17 g/mol
Appearance
White lyophilized powder
Storage (Lyophilized)
Below −20°C, desiccated, away from light and moisture
Storage (Reconstituted)
Refrigerate at 2–8°C; use within 28 days. Aliquot for extended storage below −20°C.
Shelf Life
24 months from manufacture date
Third-Party Verified
Certificate of Analysis
99.67%
PURITY
PT-141 · Batch A
TAP TO VIEW FULL COA
Batch Analysis Report
Lot Number
PLQ-PT141-2601-A
Labeled Amount
10mg
Actual Amount
10.48mg
Testing Date
01/16/2026
Tested By
Apex Analytics Lab (Third-Party)
Methods
HPLC · LC-MS · NMR · FTIR
Full COA documentation is included with every order. COAs are batch-specific and reflect the exact lot shipped. Independent third-party verification ensures unbiased purity and identity confirmation.
Protocol
Storage & Handling
Long-Term Storage
Store lyophilized peptide at −20°C. Under these conditions the product remains stable for up to 24 months from the date of manufacture.
After Reconstitution
Once reconstituted, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles as this may degrade compound integrity.
Shipping Conditions
All orders ship in insulated packaging with cooling packs to maintain the cold chain during transit. Free on every order, no minimum required.
Support
Frequently Asked Questions
PT-141 (bremelanotide) is derived from Melanotan II, a synthetic analog of alpha-MSH. Researchers identified the cyclic heptapeptide core responsible for CNS activity and developed PT-141 to act centrally through melanocortin receptors rather than peripherally through vascular mechanisms.
PDE5 inhibitors act peripherally through vascular smooth muscle relaxation. PT-141 acts centrally via CNS melanocortin receptor pathways (MC3R/MC4R) in hypothalamic arousal circuits — making it relevant to research examining CNS-mediated aspects of sexual response rather than peripheral vascular effects.
Bremelanotide (PT-141) received FDA approval as Vyleesi® for hypoactive sexual desire disorder (HSDD) in premenopausal women. Our research-grade PT-141 is not equivalent to this pharmaceutical product and is strictly for in vitro laboratory research. Not for human or animal consumption.
Add bacteriostatic water slowly along the vial wall, gently swirl until dissolved. PT-141 dissolves readily. Use our Reconstitution Calculator for volume guidance based on your desired research concentration.
Our PT-141 is verified at ≥98% purity via third-party HPLC analysis. The current batch is confirmed at 99.67% by Apex Analytics Lab. A full COA ships with every order.
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