Healing & Recovery
Epithalon
10mg / vial
A synthetic tetrapeptide analog (Ala–Glu–Asp–Gly) of a naturally occurring pineal peptide. Studied for telomere maintenance and telomerase activity in cell models, circadian rhythm and melatonin-related signaling, oxidative stress responses, cellular aging markers and senescence regulation, and immune function and inflammatory responses.
$89.99
Size
≥98% Purity
Third-party verified
Cold-Chain Shipping
Free on every order
COA Included
HPLC · LC-MS · NMR
Same-Day Shipping
Orders before 1PM EST
For Research Use Only. Not for human or animal consumption. Not a drug, food, or cosmetic. For in vitro laboratory research by qualified researchers only.
Areas of Investigation
Research Applications
Longevity
Telomere Maintenance & Telomerase Activity
Studied for its ability to activate telomerase (hTERT) enzyme expression in somatic cells, with research examining telomere length preservation and cellular replicative capacity markers in aging cell models.
Sleep
Circadian Rhythm & Melatonin Signaling
Investigated as a synthetic analog of a naturally occurring pineal gland peptide, with research examining melatonin secretion restoration and circadian rhythm normalization in aged animal models.
Protection
Oxidative Stress & Cellular Aging
Researched for antioxidant signaling and reduction of oxidative damage markers, including lipid peroxidation and cellular senescence parameters in aging research contexts.
Immunity
Immune Function Modulation
Examined for effects on T-lymphocyte activity, natural killer cell function, and cytokine profiles in aged immune system models.
Aging
Longevity Research
Used extensively in lifespan and healthspan research protocols, with preclinical data examining effects on median and maximum lifespan markers in animal models.
Technical Data
Compound Profile
Full compound characterization including molecular structure, physical properties, storage requirements, and stability data for research use.
≥98% Purity Guaranteed
HPLC · LC-MS · Third-Party Verified
Sequence
Ala-Glu-Asp-Gly
Molecular Formula
C₁₄H₂₂N₄O₉
Molecular Weight
390.35 g/mol
Appearance
White lyophilized powder
Storage (Lyophilized)
Below −20°C, desiccated, away from light and moisture
Storage (Reconstituted)
Refrigerate at 2–8°C; use within 28 days. Aliquot for extended storage below −20°C.
Shelf Life
24 months from manufacture date
Third-Party Verified
Certificate of Analysis
99.5%
PURITY
Epithalon · Batch A
TAP TO VIEW FULL COA
Batch Analysis Report
Lot Number
PLQ-EPIT-2601-A
Labeled Amount
10mg
Actual Amount
10.61mg
Testing Date
01/22/2026
Tested By
Apex Analytics Lab (Third-Party)
Methods
HPLC · LC-MS · NMR · FTIR
Full COA documentation is included with every order. COAs are batch-specific and reflect the exact lot shipped. Independent third-party verification ensures unbiased purity and identity confirmation.
Protocol
Storage & Handling
Long-Term Storage
Store lyophilized peptide at −20°C. Under these conditions the product remains stable for up to 24 months from the date of manufacture.
After Reconstitution
Once reconstituted, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles as this may degrade compound integrity.
Shipping Conditions
All orders ship in insulated packaging with cooling packs to maintain the cold chain during transit. Free on every order, no minimum required.
Support
Frequently Asked Questions
Epithalon (also spelled epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) that replicates the active sequence of epithalamin, a naturally occurring peptide isolated from the pineal gland by Russian scientist Dr. Vladimir Khavinson. It has been studied extensively in Russia since the 1980s in longevity and aging research.
Research has demonstrated that epithalon can activate telomerase (hTERT) in somatic cells, potentially supporting telomere length maintenance in cell aging models. This mechanism has made it a subject of active interest in longevity and cellular aging research, though mechanistic details continue to be studied.
As a small tetrapeptide, epithalon has excellent chemical stability. Lyophilized epithalon stored below −20°C is stable for 24 months. Once reconstituted, store at 2–8°C and use within 28 days.
Epithalon is a small tetrapeptide that dissolves readily in bacteriostatic water. Add water slowly along the vial wall, gently swirl until dissolved. Use our Reconstitution Calculator for volume guidance.
Our epithalon is verified at ≥98% purity via third-party HPLC analysis. The current batch is confirmed at 99.5% by Apex Analytics Lab — one of our highest-purity compounds. A full COA ships with every order.
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