Weight Loss
Retatrutide
5mg / vial
A synthetic triple-receptor agonist targeting GLP-1, GIP, and glucagon pathways. Researched for body-weight reduction, glucose regulation, and energy expenditure in obesity models. Combined GLP-1/GIP signaling is examined for glycemic control, while glucagon receptor activation is studied for hepatic glucose output and lipid metabolism effects.
$99.99
Size
≥98% Purity
Third-party verified
Cold-Chain Shipping
Free on every order
COA Included
HPLC · LC-MS · NMR
Same-Day Shipping
Orders before 1PM EST
For Research Use Only. Not for human or animal consumption. Not a drug, food, or cosmetic. For in vitro laboratory research by qualified researchers only.
Areas of Investigation
Research Applications
Triple Action
Triple Receptor Agonism
The first triple-acting peptide targeting GLP-1, GIP, and glucagon receptors simultaneously for synergistic metabolic effects.
Weight Loss
Body Weight Reduction
Demonstrated substantial weight loss in Phase II trials, with some participants achieving over 24% body weight reduction.
Fat Burning
Energy Expenditure
Glucagon receptor activation is studied for its potential to increase thermogenesis and fat oxidation.
Blood Sugar
Glucose Regulation
Investigated for glucose-lowering effects through combined GLP-1 and GIP receptor activation.
Liver Health
Liver Health
Under evaluation for effects on metabolic dysfunction-associated steatotic liver disease in clinical trials.
Technical Data
Compound Profile
Full compound characterization including molecular structure, physical properties, storage requirements, and stability data for research use.
≥98% Purity Guaranteed
HPLC · LC-MS · Third-Party Verified
Molecular Formula
C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight
4,731.33 g/mol
Appearance
White lyophilized powder
Storage (Lyophilized)
Below −20°C, desiccated, away from light and moisture
Storage (Reconstituted)
Refrigerate at 2–8°C; use within 28 days. Protect from light.
Shelf Life
24 months from manufacture date
Third-Party Verified
Certificate of Analysis
99.4%
PURITY
Retatrutide · Batch A
TAP TO VIEW FULL COA
Batch Analysis Report
Lot Number
PLQ-RETA-2601-A
Labeled Amount
5mg
Actual Amount
5.29mg
Testing Date
01/22/2026
Tested By
Apex Analytics Lab (Third-Party)
Methods
HPLC · LC-MS · NMR · FTIR
Full COA documentation is included with every order. COAs are batch-specific and reflect the exact lot shipped. Independent third-party verification ensures unbiased purity and identity confirmation.
Protocol
Storage & Handling
Long-Term Storage
Store lyophilized peptide at −20°C. Under these conditions the product remains stable for up to 24 months from the date of manufacture.
After Reconstitution
Once reconstituted, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles as this may degrade compound integrity.
Shipping Conditions
All orders ship in insulated packaging with cooling packs to maintain the cold chain during transit. Free on every order, no minimum required.
Support
Frequently Asked Questions
Semaglutide is a selective GLP-1 agonist. Tirzepatide adds GIP co-activation. Retatrutide extends further with glucagon receptor agonism — making it a triple receptor compound. Phase II clinical data showing 24%+ weight loss over 48 weeks positions it as a significant compound for obesity and metabolic mechanism research.
Glucagon receptor agonism stimulates hepatic glucose output and fatty acid oxidation, and is studied for increasing basal metabolic rate. In retatrutide, GLP-1 co-activation counterbalances the hyperglycemic effects of glucagon, producing net metabolic benefit studied across preclinical and Phase II research.
No. Retatrutide is an investigational compound that has completed Phase II clinical trials but has not received FDA approval. Our product is strictly research-grade, for in vitro laboratory use only by qualified researchers. Not for human or animal consumption.
Add bacteriostatic water slowly along the vial wall, gently swirl until dissolved, and do not shake. Store reconstituted solution at 2–8°C, protected from light, and use within 28 days.
Our retatrutide is verified at ≥98% purity via third-party HPLC analysis. The current batch is confirmed at 99.4% by Apex Analytics Lab. A full COA ships with every order.
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