Anti-Aging
NAD+
500mg / vial
Nicotinamide adenine dinucleotide in its oxidized form. A central pyridine nucleotide cofactor researched for its roles in cellular redox reactions, ATP production via glycolysis and the citric acid cycle, sirtuin and PARP activation for DNA repair, and connections between NAD+ metabolism and cellular aging markers.
$99.99
Size
≥98% Purity
Third-party verified
Cold-Chain Shipping
Free on every order
COA Included
HPLC · LC-MS · NMR
Same-Day Shipping
Orders before 1PM EST
For Research Use Only. Not for human or animal consumption. Not a drug, food, or cosmetic. For in vitro laboratory research by qualified researchers only.
Areas of Investigation
Research Applications
Energy
Cellular Energy Metabolism
Essential cofactor in glycolysis, the citric acid cycle, and oxidative phosphorylation, the primary pathways cells use to produce energy.
DNA Repair
DNA Repair & Genomic Stability
Required by PARP enzymes for DNA damage detection and repair, supporting genomic integrity.
Longevity
Sirtuin Activation & Longevity
Serves as the essential substrate for sirtuin enzymes (SIRT1-7), which regulate inflammation, stress response, and metabolic adaptation.
Mitochondria
Mitochondrial Function
Studied for its role in maintaining mitochondrial health and bioenergetic capacity, both of which decline with age.
Technical Data
Compound Profile
Full compound characterization including molecular structure, physical properties, storage requirements, and stability data for research use.
≥98% Purity Guaranteed
HPLC · LC-MS · Third-Party Verified
Molecular Formula
C₂₁H₂₇N₇O₁₄P₂
Molecular Weight
663.43 g/mol
Appearance
White to off-white lyophilized powder
Storage (Lyophilized)
Below −20°C, desiccated, away from light and moisture
Storage (Reconstituted)
Refrigerate at 2–8°C; use within 14 days. Protect from light. NAD+ is oxidation-sensitive — minimize air exposure.
Shelf Life
24 months from manufacture date (lyophilized, sealed)
Third-Party Verified
Certificate of Analysis
99.9%
PURITY
NAD+ · Batch A
TAP TO VIEW FULL COA
Batch Analysis Report
Lot Number
PLQ-NAD-2601-A
Labeled Amount
500mg
Actual Amount
500.61mg
Testing Date
01/22/2026
Tested By
Apex Analytics Lab (Third-Party)
Methods
HPLC · LC-MS · NMR · FTIR
Full COA documentation is included with every order. COAs are batch-specific and reflect the exact lot shipped. Independent third-party verification ensures unbiased purity and identity confirmation.
Protocol
Storage & Handling
Long-Term Storage
Store lyophilized peptide at −20°C. Under these conditions the product remains stable for up to 24 months from the date of manufacture.
After Reconstitution
Once reconstituted, store at 4°C and use within 30 days. Avoid repeated freeze-thaw cycles as this may degrade compound integrity.
Shipping Conditions
All orders ship in insulated packaging with cooling packs to maintain the cold chain during transit. Free on every order, no minimum required.
Support
Frequently Asked Questions
No — NAD+ is a dinucleotide coenzyme, not a peptide. It consists of two nucleotides joined by phosphate groups. Despite not being a peptide, it plays foundational roles in cellular energy metabolism, DNA repair, and sirtuin activation — making it a central subject in aging, metabolic disease, and neuroprotection research.
NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are NAD+ precursors that are converted to NAD+ intracellularly. Research-grade NAD+ is the direct coenzyme form. Studies using NAD+ directly examine its effects without the conversion step, while NMN/NR research focuses on the precursor pathway and bioavailability of intracellular NAD+ restoration.
Intracellular NAD+ levels decline significantly with aging due to increased PARP activity consuming NAD+ for DNA repair, CD38 upregulation as an NAD+ hydrolase, and decreased biosynthesis. This decline impairs sirtuin activity, mitochondrial function, and DNA repair capacity — making NAD+ repletion a central focus in aging and metabolic disease research.
Add sterile or bacteriostatic water slowly along the vial wall. NAD+ dissolves readily but is sensitive to oxidation — minimize air exposure once reconstituted. Store at 2–8°C protected from light and use within 14 days. Aliquot into small volumes to reduce repeated exposure to air.
Our NAD+ is verified at ≥98% purity via third-party HPLC analysis. The current batch is confirmed at 99.9% by Apex Analytics Lab, with actual content of 500.61mg in a labeled 500mg vial. A full COA ships with every order.